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Either Rap1 or Cdc13 can protect telomeric single-stranded 3′ overhangs from degradation in vitro

Telomeres, the DNA-protein structures capping the ends of linear chromosomes, are important for regulating replicative senescence and maintaining genome stability. Telomeres consist of G-rich repetitive sequences that end in a G-rich single-stranded (ss) 3′ overhang, which is vital for telomere func...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Runnberg, Rikard, Narayanan, Saishyam, Itriago, Humberto, Cohn, Marita
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915718/
https://ncbi.nlm.nih.gov/pubmed/31844093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55482-3
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