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Melatonin Protects Intervertebral Disc from Degeneration by Improving Cell Survival and Function via Activation of the ERK1/2 Signaling Pathway

Melatonin, a neuroendocrine hormone secreted by the pineal body, has a positive effect on intervertebral disc degeneration. The present study is aimed at investigating the biological role of melatonin in intervertebral disc degeneration and its underlying mechanism. A human nucleus pulposus cell (NP...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oxid Med Cell Longev
Main Authors: Ge, Jun, Zhou, Quan, Niu, Junjie, Wang, Yingjie, Yan, Qi, Wu, Cenhao, Qian, Jiale, Yang, Huilin, Zou, Jun
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914917/
https://ncbi.nlm.nih.gov/pubmed/31885798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5120275
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