Mate pair sequencing outperforms fluorescence in situ hybridization in the genomic characterization of multiple myeloma

Fluorescence in situ hybridization (FISH) is currently the gold-standard assay to detect recurrent genomic abnormalities of prognostic significance in multiple myeloma (MM). Since most translocations in MM involve a position effect with heterogeneous breakpoints, we hypothesize that FISH has the pot...

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Publicado en:Blood Cancer J
Main Authors: Smadbeck, James, Peterson, Jess F., Pearce, Kathryn E., Pitel, Beth A., Figueroa, Andrea Lebron, Timm, Michael, Jevremovic, Dragan, Shi, Min, Stewart, A. Keith, Braggio, Esteban, Riggs, Daniel L., Bergsagel, P. Leif, Vasmatzis, George, Kearney, Hutton M., Hoppman, Nicole L., Ketterling, Rhett P., Kumar, Shaji, Rajkumar, S. Vincent, Greipp, Patricia T., Baughn, Linda B.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914798/
https://ncbi.nlm.nih.gov/pubmed/31844041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-019-0255-z
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