Mate pair sequencing outperforms fluorescence in situ hybridization in the genomic characterization of multiple myeloma

Fluorescence in situ hybridization (FISH) is currently the gold-standard assay to detect recurrent genomic abnormalities of prognostic significance in multiple myeloma (MM). Since most translocations in MM involve a position effect with heterogeneous breakpoints, we hypothesize that FISH has the pot...

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Pubblicato in:Blood Cancer J
Autori principali: Smadbeck, James, Peterson, Jess F., Pearce, Kathryn E., Pitel, Beth A., Figueroa, Andrea Lebron, Timm, Michael, Jevremovic, Dragan, Shi, Min, Stewart, A. Keith, Braggio, Esteban, Riggs, Daniel L., Bergsagel, P. Leif, Vasmatzis, George, Kearney, Hutton M., Hoppman, Nicole L., Ketterling, Rhett P., Kumar, Shaji, Rajkumar, S. Vincent, Greipp, Patricia T., Baughn, Linda B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914798/
https://ncbi.nlm.nih.gov/pubmed/31844041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-019-0255-z
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