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SAM-VI riboswitch structure and signature for ligand discrimination

Riboswitches are metabolite-sensing, conserved domains located in non-coding regions of mRNA that are central to regulation of gene expression. Here we report the first three-dimensional structure of the recently discovered S-adenosyl-L-methionine responsive SAM-VI riboswitch. SAM-VI adopts a unique...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Sun, Aiai, Gasser, Catherina, Li, Fudong, Chen, Hao, Mair, Stefan, Krasheninina, Olga, Micura, Ronald, Ren, Aiming
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914780/
https://ncbi.nlm.nih.gov/pubmed/31844059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13600-9
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