The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability

Ubiquitin-specific protease (USP) 6 is a hominoid deubiquitinating enzyme previously implicated in intellectual disability and autism spectrum disorder. Although these findings link USP6 to higher brain function, potential roles for USP6 in cognition have not been investigated. Here, we report that...

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Publicado no:PLoS Biol
Main Authors: Zeng, Fanwei, Ma, Xuehai, Zhu, Lin, Xu, Qiang, Zeng, Yuzhe, Gao, Yue, Li, Guilin, Guo, Tiantian, Zhang, Haibin, Tang, Xiaoyan, Wang, Ziqiang, Ye, Zesen, Zheng, Liangkai, Zhang, Hongfeng, Zheng, Qiuyang, Li, Kunping, Lu, Jinfang, Qi, Xueting, Luo, Hong, Zhang, Xian, Wang, Zhanxiang, Zhou, Yulin, Yao, Yi, Ke, Rongqin, Zhou, Ying, Liu, Yan, Sun, Hao, Huang, Timothy, Shao, Zhicheng, Xu, Huaxi, Wang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913916/
https://ncbi.nlm.nih.gov/pubmed/31841517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000525
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