Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation

Pursuing on our efforts toward searching for efficient hCA IX and hCA XII inhibitors, herein we report the design and synthesis of new sets of benzofuran-based sulphonamides (4a,b, 5a,b, 9a–c, and 10a–d), featuring the zinc anchoring benzenesulfonamide moiety linked to a benzofuran tail via a hydraz...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Abdelrahman, Mohamed A., Eldehna, Wagdy M., Nocentini, Alessio, Ibrahim, Hany S., Almahli, Hadia, Abdel-Aziz, Hatem A., Abou-Seri, Sahar M., Supuran, Claudiu T.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913630/
https://ncbi.nlm.nih.gov/pubmed/31809607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1697250
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