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Beyond JAK-STAT: novel therapeutic targets in Ph-negative MPN

The Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) share a common pathobiology of constitutive activation of the JAK and STAT pathway, despite having the 3 distinct phenotypes of essential thrombocythemia, polycythemia vera, and primary myelofibrosis. Targeting the JAK-STAT pat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hematology Am Soc Hematol Educ Program
Prif Awdur: Gerds, Aaron T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913459/
https://ncbi.nlm.nih.gov/pubmed/31808852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/hematology.2019000048
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