Triterpenoid Saponins from Anemone flaccida Suppress Tumor Cell Proliferation by Regulating MAPK, PD1/PDL1, and STAT3 Signaling Pathways and Altering Cancer Metabolism

PURPOSE: Natural triterpenoid saponins isolated from Anemone flaccida Fr. Schmidt have exhibited anti-cancer properties and exerted remarkable inhibitory effects on tumor growth. Herein, we investigated the potential mechanism involved in the suppression of hepatocellular carcinoma (HCC) development...

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Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Han, Lintao, Yao, Shiqi, Cao, Sa, Mo, Guoyan, Li, Jingjing, Cao, Yan, Huang, Fang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2019
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913295/
https://ncbi.nlm.nih.gov/pubmed/31849495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S212666
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