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Structural transition of replicable RNAs during in vitro evolution with Qβ replicase

Single-stranded RNAs (ssRNAs) are utilized as genomes in some viruses and also in experimental models of ancient life-forms, owing to their simplicity. One of the largest problems for ssRNA replication is the formation of double-stranded RNA (dsRNA), a dead-end product for ssRNA replication. A possi...

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Publicado en:RNA
Autores principales: Mizuuchi, Ryo, Usui, Kimihito, Ichihashi, Norikazu
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913131/
https://ncbi.nlm.nih.gov/pubmed/31690585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.073106.119
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