Combinatorial selection for replicable RNA by Qβ replicase while maintaining encoded gene function

Construction of a complex artificial self-replication system is challenging in the field of in vitro synthetic biology. Recently, we developed a translation-coupled RNA replication system, wherein an artificial genomic RNA replicates with the Qβ RNA replicase gene encoded on itself. The challenge is...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Yumura, Mio, Yamamoto, Natsuko, Yokoyama, Katsushi, Mori, Hirotada, Yomo, Tetsuya, Ichihashi, Norikazu
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362092/
https://ncbi.nlm.nih.gov/pubmed/28328998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174130
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