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pH Responsive 5-Fluorouracil Loaded Biocompatible Nanogels For Topical Chemotherapy of Aggressive Melanoma

Combating melanoma via topical route is a highly challenging task due to low selectivity, poor efficacy and impeding biological environment of the skin. In the present study, we engineered a chitosan based pH responsive biodegradable nanogel (FCNGL), encapsulated with 5-FU that was effective even at...

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Detalhes bibliográficos
Publicado no:Colloids Surf B Biointerfaces
Main Authors: Sahu, Prashant, Kashaw, Sushil K., Sau, Samaresh, Kushwah, Varun, Jain, Sanyog, Agrawal, Ram K., Iyer, Arun K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912856/
https://ncbi.nlm.nih.gov/pubmed/30465998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.colsurfb.2018.11.018
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