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Akt1 and Akt2 Isoforms Play Distinct Roles in Regulating the Development of Inflammation and Fibrosis Associated with Alcoholic Liver Disease

Akt kinase isoforms (Akt1, Akt2, and Akt3) have generally been thought to play overlapping roles in phosphoinositide 3-kinase (PI3K)-mediated-signaling. However, recent studies have suggested that they display isoform-specific roles in muscle and fat. To determine whether such isoform-specificity is...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Reyes-Gordillo, Karina, Shah, Ruchi, Arellanes-Robledo, Jaime, Cheng, Ying, Ibrahim, Joseph, Tuma, Pamela L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912497/
https://ncbi.nlm.nih.gov/pubmed/31671832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111337
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