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Akt1 and Akt2 Isoforms Play Distinct Roles in Regulating the Development of Inflammation and Fibrosis Associated with Alcoholic Liver Disease

Akt kinase isoforms (Akt1, Akt2, and Akt3) have generally been thought to play overlapping roles in phosphoinositide 3-kinase (PI3K)-mediated-signaling. However, recent studies have suggested that they display isoform-specific roles in muscle and fat. To determine whether such isoform-specificity is...

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Pubblicato in:Cells
Autori principali: Reyes-Gordillo, Karina, Shah, Ruchi, Arellanes-Robledo, Jaime, Cheng, Ying, Ibrahim, Joseph, Tuma, Pamela L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912497/
https://ncbi.nlm.nih.gov/pubmed/31671832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111337
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