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Development of Oxadiazole-Based ODZ10117 as a Small-Molecule Inhibitor of STAT3 for Targeted Cancer Therapy

Persistently activated STAT3 is a promising target for a new class of anticancer drug development and cancer therapy, as it is associated with tumor initiation, progression, malignancy, drug resistance, cancer stem cell properties, and recurrence. Here, we discovered 3-(2,4-dichloro-phenoxymethyl)-5...

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Podrobná bibliografie
Vydáno v:J Clin Med
Hlavní autoři: Kim, Byung-Hak, Lee, Haeri, Song, Yeonghun, Park, Joon-Suk, Gadhe, Changdev G., Choi, Jiwon, Lee, Chung-Gi, Pae, Ae Nim, Kim, Sanghee, Ye, Sang-Kyu
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912340/
https://ncbi.nlm.nih.gov/pubmed/31684051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8111847
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