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Rewiring of Cancer Cell Metabolism by Mitochondrial VDAC1 Depletion Results in Time-Dependent Tumor Reprogramming: Glioblastoma as a Proof of Concept

Reprograming of the metabolism of cancer cells is an event recognized as a hallmark of the disease. The mitochondrial gatekeeper, voltage-dependent anion channel 1 (VDAC1), mediates transport of metabolites and ions in and out of mitochondria, and is involved in mitochondria-mediated apoptosis. Here...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Arif, Tasleem, Stern, Oriel, Pittala, Srinivas, Chalifa-Caspi, Vered, Shoshan-Barmatz, Varda
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912264/
https://ncbi.nlm.nih.gov/pubmed/31661894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111330
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