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Mitochondrial VDAC1 Silencing Leads to Metabolic Rewiring and the Reprogramming of Tumour Cells into Advanced Differentiated States

Oncogenic properties, along with the metabolic reprogramming necessary for tumour growth and motility, are acquired by cancer cells. Thus, tumour metabolism is becoming a target for cancer therapy. Here, cancer cell metabolism was tackled by silencing the expression of voltage-dependent anion channe...

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Dades bibliogràfiques
Publicat a:Cancers (Basel)
Autors principals: Arif, Tasleem, Paul, Avijit, Krelin, Yakov, Shteinfer-Kuzmine, Anna, Shoshan-Barmatz, Varda
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316808/
https://ncbi.nlm.nih.gov/pubmed/30544833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10120499
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