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Mitochondrial VDAC1 Silencing Leads to Metabolic Rewiring and the Reprogramming of Tumour Cells into Advanced Differentiated States

Oncogenic properties, along with the metabolic reprogramming necessary for tumour growth and motility, are acquired by cancer cells. Thus, tumour metabolism is becoming a target for cancer therapy. Here, cancer cell metabolism was tackled by silencing the expression of voltage-dependent anion channe...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Arif, Tasleem, Paul, Avijit, Krelin, Yakov, Shteinfer-Kuzmine, Anna, Shoshan-Barmatz, Varda
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316808/
https://ncbi.nlm.nih.gov/pubmed/30544833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10120499
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