Distinct Roles of Interferon Alpha and Beta in Controlling Chikungunya Virus Replication and Modulating Neutrophil-Mediated Inflammation

Type I interferons (IFNs) are key mediators of the innate immune response. Although members of this family of cytokines signal through a single shared receptor, biochemical and functional variation exists in response to different IFN subtypes. While previous work has demonstrated that type I IFNs ar...

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Vydáno v:J Virol
Hlavní autoři: Cook, Lindsey E., Locke, Marissa C., Young, Alissa R., Monte, Kristen, Hedberg, Matthew L., Shimak, Raeann M., Sheehan, Kathleen C. F., Veis, Deborah J., Diamond, Michael S., Lenschow, Deborah J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912113/
https://ncbi.nlm.nih.gov/pubmed/31619554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00841-19
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