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Interferon Regulatory Factor 1 Protects against Chikungunya Virus-Induced Immunopathology by Restricting Infection in Muscle Cells

The innate immune system protects cells against viral pathogens in part through the autocrine and paracrine actions of alpha/beta interferon (IFN-α/β) (type I), IFN-γ (type II), and IFN-λ (type III). The transcription factor interferon regulatory factor 1 (IRF-1) has a demonstrated role in shaping i...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Nair, Sharmila, Poddar, Subhajit, Shimak, Raeann M., Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660487/
https://ncbi.nlm.nih.gov/pubmed/28835505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01419-17
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