Pharmacokinetic Parameters of Quinine in Healthy Subjects and in Patients with Uncomplicated Malaria in Nigeria: Analysis of Data using a Population Approach

BACKGROUND: The varied disposition of the antimalarial quinine partly explains its poor tolerance and toxicity in humans. OBJECTIVE: Using a population approach, the disposition of quinine in healthy subjects and patients with acute uncomplicated symptomatic malaria from Nigeria was re-examined with...

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Publicado en:Curr Ther Res Clin Exp
Autores principales: Adehin, Ayorinde, Igbinoba, Sharon I., Soyinka, Julius O., Onyeji, Cyprian O., Babalola, Chinedum P., Bolaji, Oluseye O.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911901/
https://ncbi.nlm.nih.gov/pubmed/31871506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.curtheres.2019.100567
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