Mcl-1 interacts with Akt to promote lung cancer progression

Mcl-1 is a unique antiapoptotic Bcl-2 family protein that functions as a gatekeeper in manipulating apoptosis and survival in cancer cells. Akt is an oncogenic kinase that regulates multiple cellular functions and its activity is significantly elevated in human cancers. Here we discovered a cross-ta...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Chen, Guo, Park, Dongkyoo, Magis, Andrew T., Behera, Madhusmita, Ramalingam, Suresh S., Owonikoko, Taofeek K., Sica, Gabriel L., Ye, Keqiang, Zhang, Chao, Chen, Zhengjia, Curran, Walter J., Deng, Xingming
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911632/
https://ncbi.nlm.nih.gov/pubmed/31662324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0950
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