Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus

Neutrophil dysregulation is implicated in the pathogenesis of systemic lupus erythematosus (SLE). SLE is characterized by elevated levels of a pathogenic neutrophil subset known as low-density granulocytes (LDGs). The origin and phenotypic, functional, and pathogenic heterogeneity of LDGs remain to...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Main Authors: Mistry, Pragnesh, Nakabo, Shuichiro, O’Neil, Liam, Goel, Rishi R., Jiang, Kan, Carmona-Rivera, Carmelo, Gupta, Sarthak, Chan, Diana W., Carlucci, Philip M., Wang, Xinghao, Naz, Faiza, Manna, Zerai, Dey, Amit, Mehta, Nehal N., Hasni, Sarfaraz, Dell’Orso, Stefania, Gutierrez-Cruz, Gustavo, Sun, Hong-Wei, Kaplan, Mariana J.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2019
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911190/
https://ncbi.nlm.nih.gov/pubmed/31754025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908576116
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