Peptide hormone ELABELA enhances extravillous trophoblast differentiation, but placenta is not the major source of circulating ELABELA in pregnancy

Preeclampsia is a frequent gestational hypertensive disorder with equivocal pathophysiology. Knockout of peptide hormone ELABELA (ELA) has been shown to cause preeclampsia-like symptoms in mice. However, the role of ELA in human placentation and whether ELA is involved in the development of preeclam...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Georgiadou, Danai, Boussata, Souad, Ranzijn, Willemijn H. M., Root, Leah E. A., Hillenius, Sanne, bij de Weg, Jeske M., Abheiden, Carolien N. H., de Boer, Marjon A., de Vries, Johanna I. P., Vrijkotte, Tanja G. M., Lambalk, Cornelis B., Kuijper, Esther A. M., Afink, Gijs B., van Dijk, Marie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911039/
https://ncbi.nlm.nih.gov/pubmed/31836787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55650-5
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