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A recurrent GARS mutation causes distal hereditary motor neuropathy

We found a p.Gly327Arg mutation in GARS in two unrelated women, both of whom had a similar phenotype - motor weakness that began in late childhood, distal weakness in the arms and legs, a motor greater than sensory neuropathy with slowing of motor and not sensory conduction velocities. A de novo mut...

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Détails bibliographiques
Publié dans:J Peripher Nerv Syst
Auteurs principaux: Lee, Diana C., Meyer-Schuman, Rebecca, Bacon, Chelsea, Shy, Michael E., Antonellis, Anthony, Scherer, Steven S.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910989/
https://ncbi.nlm.nih.gov/pubmed/31628756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jns.12353
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