Intra-individual correlations between quantitative THK-5351 PET and MRI-derived cortical volume in Alzheimer’s disease differ according to disease severity and amyloid positivity

PURPOSE: To assess the in vivo whole-brain relationship between uptake of [(18)F]THK-5351 on PET and cortical atrophy on structural MRI according to the presence and severity of Alzheimer’s disease (AD). MATERIALS AND METHODS: Sixty-five participants (21 normal controls, 32 mild cognitive impairment...

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Udgivet i:PLoS One
Main Authors: Park, Ji Eun, Yun, Jessica, Kim, Sang Joon, Shim, Woo Hyun, Oh, Jungsu S., Oh, Minyoung, Roh, Jee Hoon, Seo, Sang Won, Oh, Seung Jun, Kim, Jae Seung
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910674/
https://ncbi.nlm.nih.gov/pubmed/31834916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226265
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