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Role of PKC and ERK Signaling in Epidermal Blistering and Desmosome Regulation in Pemphigus
Desmosomes reinforce cohesion of epithelial cells at the interface between adjacent cells. They include the cadherin-type adhesion molecules desmoglein 1 (Dsg1) and Dsg3. Pemphigus vulgaris (PV) is an autoimmune disease in which circulating autoantibodies (PV-IgG) targeting Dsg1 and 3 cause characte...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6910072/ https://ncbi.nlm.nih.gov/pubmed/31867019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02883 |
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