HPV 16 E6/E7 up-regulate the expression of both HIF-1α and GLUT1 by inhibition of RRAD and activation of NF-κB in lung cancer cells

Chronic infection of HPV16 E6/E7 is frequently associated with lung cancers, especially in non-smokers and in Asians. In our previous studies, we found that HPV16 E6/E7 up-regulated HIF-1α at protein level and further up-regulated GLUT1 at both protein and mRNA levels in well-established lung cancer...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Gu, Na-Jin, Wu, Ming-Zhe, He, Ling, Wang, Xu-Bo, Wang, Shiyu, Qiu, Xue-Shan, Wang, En-Hua, Wu, Guang-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909954/
https://ncbi.nlm.nih.gov/pubmed/31839825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.37070
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