Suppression of Th1-Mediated Keratoconjunctivitis Sicca by Lifitegrast

Purpose: Increased interferon gamma (IFN-γ) expression in dry eye causes ocular surface epithelial disease termed keratoconjunctivitis sicca (KCS). The purpose of this study was to investigated the effects of the LFA-1 antagonist, lifitegrast, in a mouse desiccating stress (DS) dry eye model that de...

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Bibliografiske detaljer
Udgivet i:J Ocul Pharmacol Ther
Main Authors: Guimaraes de Souza, Rodrigo, Yu, Zhiyuan, Stern, Michael E., Pflugfelder, Stephen C., de Paiva, Cintia S.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2018
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909696/
https://ncbi.nlm.nih.gov/pubmed/29958030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2018.0047
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