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Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference

Multiplexed single-cell RNA-seq analysis of multiple samples using pooling is a promising experimental design, offering increased throughput while allowing to overcome batch variation. To reconstruct the sample identify of each cell, genetic variants that segregate between the samples in the pool ha...

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Pubblicato in:Genome Biol
Autori principali: Huang, Yuanhua, McCarthy, Davis J., Stegle, Oliver
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909514/
https://ncbi.nlm.nih.gov/pubmed/31836005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1865-2
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