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AMPK leads to phosphorylation of the transcription factor Nrf2, tuning transactivation of selected target genes

The transcription factor Nrf2 (nuclear factor (erythroid-derived 2)-like 2) and the kinase AMPK (AMP-activated protein kinase) participate in the cellular adaptive response to redox or energy stress. Despite accumulating evidence for positive cooperativity between both proteins, information about di...

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Publicat a:Redox Biol
Autors principals: Matzinger, Manuel, Fischhuber, Katrin, Pölöske, Daniel, Mechtler, Karl, Heiss, Elke H.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909106/
https://ncbi.nlm.nih.gov/pubmed/31805502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101393
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