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Synthesis and preclinical validation of novel P2Y1 receptor ligands as a potent anti-prostate cancer agent
Purinergic receptor is a potential drug target for neuropathic pain, Alzheimer disease, and prostate cancer. Focusing on the structure-based ligand discovery, docking analysis on the crystal structure of P2Y(1) receptor (P2Y(1)R) with 923 derivatives of 1-indolinoalkyl 2-phenolic compound is perform...
Gorde:
| Argitaratua izan da: | Sci Rep |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group UK
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6908675/ https://ncbi.nlm.nih.gov/pubmed/31831761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55194-8 |
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