Characterization of the enzymatic activity of the serine protease domain of Factor VII activating protease (FSAP)

Factor VII (FVII) activating protease (FSAP) is a circulating serine protease. Human genetic studies, based on the Marburg I (MI) (Gly221Glu, chymotrypsin numbering system) polymorphism, implicate FSAP in the pathogenesis of many diseases. Here, we describe the molecular and functional changes cause...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nielsen, Nis V., Roedel, Elfie, Manna, Dipankar, Etscheid, Michael, Morth, Jens Preben, Kanse, Sandip M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908674/
https://ncbi.nlm.nih.gov/pubmed/31831842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55531-x
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