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Inhibition of tRNA Gene Transcription by the Immunosuppressant Mycophenolic Acid
Mycophenolic acid (MPA) is the active metabolite of mycophenolate mofetil, a drug that is widely used for immunosuppression in organ transplantation and autoimmune diseases, as well as anticancer chemotherapy. It inhibits IMP dehydrogenase, a rate-limiting enzyme in de novo synthesis of guanidine nu...
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| Izdano u: | Mol Cell Biol |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6908259/ https://ncbi.nlm.nih.gov/pubmed/31658995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00294-19 |
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