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The CCR4-NOT Complex Maintains Stability and Transcription of rRNA Genes by Repressing Antisense Transcripts

The rRNA genes (rDNA) in eukaryotes are organized into highly repetitive gene clusters. Each organism maintains a particular number of copies, suggesting that the rDNA is actively stabilized. We previously identified about 700 Saccharomyces cerevisiae genes that could contribute to rDNA maintenance....

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Hosoyamada, Shun, Sasaki, Mariko, Kobayashi, Takehiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908257/
https://ncbi.nlm.nih.gov/pubmed/31611247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00320-19
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