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R-Loop Stabilization Represses Antisense Transcription at the Arabidopsis FLC Locus

Roles for long noncoding RNAs (lncRNAs) in gene expression are emerging, but regulation of the lncRNA itself is poorly understood. We have identified a homeodomain protein, AtNDX, that regulates COOLAIR, a set of antisense transcripts originating from the 3’ end of Arabidopsis FLOWERING LOCUS C (FLC...

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發表在:Science
Main Authors: Sun, Qianwen, Csorba, Tibor, Skourti-Stathaki, Konstantina, Proudfoot, Nicholas J., Dean, Caroline
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144995/
https://ncbi.nlm.nih.gov/pubmed/23641115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1234848
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