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KSHV activates unfolded protein response sensors but suppresses downstream transcriptional responses to support lytic replication

Herpesviruses usurp host cell protein synthesis machinery to convert viral mRNAs into proteins, and the endoplasmic reticulum (ER) to ensure proper folding, post-translational modification and trafficking of secreted and transmembrane viral proteins. Overloading ER folding capacity activates the unf...

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Bibliografski detalji
Izdano u:PLoS Pathog
Glavni autori: Johnston, Benjamin P., Pringle, Eric S., McCormick, Craig
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907875/
https://ncbi.nlm.nih.gov/pubmed/31790507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008185
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