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KSHV activates unfolded protein response sensors but suppresses downstream transcriptional responses to support lytic replication
Herpesviruses usurp host cell protein synthesis machinery to convert viral mRNAs into proteins, and the endoplasmic reticulum (ER) to ensure proper folding, post-translational modification and trafficking of secreted and transmembrane viral proteins. Overloading ER folding capacity activates the unf...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6907875/ https://ncbi.nlm.nih.gov/pubmed/31790507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008185 |
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