Therapeutic monoclonal antibody treatment protects nonhuman primates from severe Venezuelan equine encephalitis virus disease after aerosol exposure

There are no FDA licensed vaccines or therapeutics for Venezuelan equine encephalitis virus (VEEV) which causes a debilitating acute febrile illness in humans that can progress to encephalitis. Previous studies demonstrated that murine and macaque monoclonal antibodies (mAbs) provide prophylactic an...

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Publicado en:PLoS Pathog
Main Authors: Burke, Crystal W., Froude, Jeffery W., Rossi, Franco, White, Charles E., Moyer, Crystal L., Ennis, Jane, Pitt, M. Louise, Streatfield, Stephen, Jones, R. Mark, Musiychuk, Konstantin, Kervinen, Jukka, Zeitlin, Larry, Yusibov, Vidadi, Glass, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907853/
https://ncbi.nlm.nih.gov/pubmed/31790515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008157
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