Therapeutic monoclonal antibody treatment protects nonhuman primates from severe Venezuelan equine encephalitis virus disease after aerosol exposure

There are no FDA licensed vaccines or therapeutics for Venezuelan equine encephalitis virus (VEEV) which causes a debilitating acute febrile illness in humans that can progress to encephalitis. Previous studies demonstrated that murine and macaque monoclonal antibodies (mAbs) provide prophylactic an...

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Vydáno v:PLoS Pathog
Hlavní autoři: Burke, Crystal W., Froude, Jeffery W., Rossi, Franco, White, Charles E., Moyer, Crystal L., Ennis, Jane, Pitt, M. Louise, Streatfield, Stephen, Jones, R. Mark, Musiychuk, Konstantin, Kervinen, Jukka, Zeitlin, Larry, Yusibov, Vidadi, Glass, Pamela J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907853/
https://ncbi.nlm.nih.gov/pubmed/31790515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008157
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