Reversed metabolic reprogramming as a measure of cancer treatment efficacy in rat C6 glioma model

BACKGROUND: Metabolism in tumor shifts from oxidative phosphorylation to inefficient glycolysis resulting in overproduction of lactate (Warburg effect), and cancers may be effectively treated if this imbalance were corrected. The aim of this longitudinal study of glioblastoma in a rat model was to d...

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Veröffentlicht in:PLoS One
Hauptverfasser: Datta, Keshav, Lauritzen, Mette H., Merchant, Milton, Jang, Taichang, Liu, Shie-Chau, Hurd, Ralph, Recht, Lawrence, Spielman, Daniel M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907781/
https://ncbi.nlm.nih.gov/pubmed/31830049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225313
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