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Mouse APOBEC3 interferes with autocatalytic cleavage of murine leukemia virus Pr180gag-pol precursor and inhibits Pr65gag processing

Mouse APOBEC3 (mA3) inhibits murine leukemia virus (MuLV) replication by a deamination-independent mechanism in which the reverse transcription is considered the main target process. However, other steps in virus replication that can be targeted by mA3 have not been examined. We have investigated th...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: Hakata, Yoshiyuki, Li, Jun, Fujino, Takahiro, Tanaka, Yuki, Shimizu, Rie, Miyazawa, Masaaki
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907756/
https://ncbi.nlm.nih.gov/pubmed/31830125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008173
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