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Mouse APOBEC3 interferes with autocatalytic cleavage of murine leukemia virus Pr180gag-pol precursor and inhibits Pr65gag processing

Mouse APOBEC3 (mA3) inhibits murine leukemia virus (MuLV) replication by a deamination-independent mechanism in which the reverse transcription is considered the main target process. However, other steps in virus replication that can be targeted by mA3 have not been examined. We have investigated th...

詳細記述

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書誌詳細
出版年:PLoS Pathog
主要な著者: Hakata, Yoshiyuki, Li, Jun, Fujino, Takahiro, Tanaka, Yuki, Shimizu, Rie, Miyazawa, Masaaki
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907756/
https://ncbi.nlm.nih.gov/pubmed/31830125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008173
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