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Next‐generation disease modeling with direct conversion: a new path to old neurons

Within just over a decade, human reprogramming‐based disease modeling has developed from a rather outlandish idea into an essential part of disease research. While iPSCs are a valuable tool for modeling developmental and monogenetic disorders, their rejuvenated identity poses limitations for modelin...

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Bibliografiske detaljer
Udgivet i:FEBS Lett
Main Authors: Traxler, Larissa, Edenhofer, Frank, Mertens, Jerome
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907729/
https://ncbi.nlm.nih.gov/pubmed/31715002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13678
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