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The atypical cyclin-like protein Spy1 overrides p53-mediated tumour suppression and promotes susceptibility to breast tumourigenesis

BACKGROUND: Breast cancer is the most common cancer to affect women and one of the leading causes of cancer-related deaths. Proper regulation of cell cycle checkpoints plays a critical role in preventing the accumulation of deleterious mutations. Perturbations in the expression or activity of mediat...

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Vydáno v:Breast Cancer Res
Hlavní autoři: Fifield, Bre-Anne, Qemo, Ingrid, Kirou, Evie, Cardiff, Robert D., Porter, Lisa Ann
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907270/
https://ncbi.nlm.nih.gov/pubmed/31829284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-019-1211-3
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