Ifenprodil and Flavopiridol Identified by Genomewide RNA Interference Screening as Effective Drugs To Ameliorate Murine Acute Lung Injury after Influenza A H5N1 Virus Infection

Due to the limitations of effective treatments, avian influenza A H5N1 virus is the most lethal influenza virus strain that causes severe acute lung injury (ALI). To develop effective drugs ameliorating H5N1-induced ALI, we explore an RNA interference (RNAi) screening method to monitor changes in ce...

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Detalhes bibliográficos
Publicado no:mSystems
Main Authors: Zhang, Cong, Zhang, Yuqing, Qin, Yuhao, Zhang, Qingchao, Liu, Qiang, Shang, Daozhen, Lu, Huijun, Li, Xiao, Zhou, Congzhao, Huang, Fengming, Jin, Ningyi, Jiang, Chengyu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906739/
https://ncbi.nlm.nih.gov/pubmed/31822599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00431-19
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