C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis

It is important to understand how the disease process affects the metabolic pathways in amyotrophic lateral sclerosis and whether these pathways can be manipulated to ameliorate disease progression. To analyse the basis of the metabolic defect in amyotrophic lateral sclerosis we used a phenotypic me...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Allen, Scott P, Hall, Benjamin, Woof, Ryan, Francis, Laura, Gatto, Noemi, Shaw, Allan C, Myszczynska, Monika, Hemingway, Jordan, Coldicott, Ian, Willcock, Amelia, Job, Lucy, Hughes, Rachel M, Boschian, Camilla, Bayatti, Nadhim, Heath, Paul R, Bandmann, Oliver, Mortiboys, Heather, Ferraiuolo, Laura, Shaw, Pamela J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906594/
https://ncbi.nlm.nih.gov/pubmed/31647549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awz302
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