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NMDA attenuates the neurovascular response to hypercapnia in the neonatal cerebral cortex

Cortical spreading depolarization (SD) involves activation of NMDA receptors and elicit neurovascular unit dysfunction. NMDA cannot trigger SD in newborns, thus its effect on neurovascular function is not confounded by other aspects of SD. The present study investigated if NMDA affected hypercapnia-...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Remzső, Gábor, Németh, János, Tóth-Szűki, Valéria, Varga, Viktória, Kovács, Viktória, Domoki, Ferenc
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906464/
https://ncbi.nlm.nih.gov/pubmed/31827200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55468-1
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