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Molecular hydrogen alleviates asphyxia-induced neuronal cyclooxygenase-2 expression in newborn pigs

Cyclooxygenase-2 (COX-2) has an established role in the pathogenesis of hypoxic-ischemic encephalopathy (HIE). In this study we sought to determine whether COX-2 was induced by asphyxia in newborn pigs, and whether neuronal COX-2 levels were affected by H(2) treatment. Piglets were subjected to eith...

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Detalles Bibliográficos
Publicado en:Acta Pharmacol Sin
Main Authors: Varga, Viktória, Németh, János, Oláh, Orsolya, Tóth-Szűki, Valéria, Kovács, Viktória, Remzső, Gábor, Domoki, Ferenc
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289359/
https://ncbi.nlm.nih.gov/pubmed/29565041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.148
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