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Differential remodeling of the electron transport chain is required to support TLR3 and TLR4 signaling and cytokine production in macrophages

Increasing evidence suggests that mitochondria play a critical role in driving innate immune responses against bacteria and viruses. However, it is unclear if differential reprogramming of mitochondrial function contributes to the fine tuning of pathogen specific immune responses. Here, we found tha...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ahmed, Duale, Roy, David, Jaworski, Allison, Edwards, Alexander, Abizaid, Alfonso, Kumar, Ashok, Golshani, Ashkan, Cassol, Edana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906364/
https://ncbi.nlm.nih.gov/pubmed/31827178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55295-4
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